SOY CONFUSED? By Susan Malie  
     
 

Current research is confusing consumers on the role soy plays, in regards to our health. The American Association of Cancer Research states, based on epidemiological studies, that soybean protein depleted of isoflavones is more effective in preventing breast cancer. This statement suggests that isoflavones may not be as beneficial as we once thought, which is creating a concern to our customers taking soy or isoflavone supplements. 

Some research studies are even suggesting that the estrogen-like soy isoflavone may play a role in causing breast cancer. However, many of the studies done to test this hypothesis were done on women who already had breast cancer, which would not tell us if these isoflavone compounds are in fact causing cancer, due to these women already having abnormal breast tissue. This and other studies have many limitations, such as not having a control group, to test if there would have been similar results if those involved in the study remained on an isoflavone-free diet. As if this isnít confusing enough, there are recent data proving contraindicating resultsóthat soy isoflavones can help prevent breast cancer.

Some studies show long-term (over 6 weeks) exposure to soy isoflavones is when beneficial effects are noted. This is based on the fact that soy isoflavones act as either a weak estrogen or have the ability to block the effects of the estrogen hormone. A study published in a recent issue of Cancer Epidemiology found that rats chemically induced with mammary cancer had a 20% decreased incidence in these tumors when exposed to soy as their sole source of protein versus casein. There has also been a positive correlation between soy and breast tissue in young animals. 

Letís not forget that phytoestrogens have been shown to be beneficial for lowering total cholesterol and LDL or ìbadî cholesterol, and these reductions are greater in persons with abnormally high cholesterol levels. Phytoestrogens may even protect against arteriosclerosis, by interfering with the initial inflammatory process.  Isoflavone compounds have demonstrated to be beneficial regarding bone health as well, by increasing bone mineral content. In Japan, long-term consumption of soy isoflavones, naturally occurring in the food supply, have failed to result in adverse affects on this population. If soy isoflavones caused breast cancer, wouldnít there be an increased incidence in breast cancer rates throughout Japan?

Many soy supplements, not taken in excess of the amount recommended on the label, contain amounts of isoflavones easily provided in the diet. Eating 3 ounces of tofu can give you about 40-60 mg of isoflavones. Our soy protein powders (VL 962) and (VL 968) provide approximately 60 mg of total isoflavones per serving. The Nova Soy Isoflavone Tablets (VL 144) contain ~50 mg total isoflavones per tablet, and the Ultimate Soy-Spirulina powders (VL 964 & 965) contain even less, at ~36 mg of isoflavones per serving. As you can see, these are amounts that are easily obtainable from the diet. All of these soy products mentioned above are processed with a natural water wash, which retains isoflavones in their natural ratios, providing the consumer with a more natural, full-spectrum product.

So it is clear that there is still insufficient evidence involving the role of soy and its isoflavones on breast tissue. Soy still proves to be beneficial in many areas, relating to good overall health. It is not wise to discard all of our knowledge and research on soy based on a few studies with apparent limitations.  It is important that consumers understand that not every study done is 100% valid or accurate in its findings and there are always limitations to be seen. Articles relating to health must be evaluated very closely, as they can be biased depending on what methods were used, the desired outcome, and the source of funding. 

Lastly, more research needs to be done regarding the role of soy and breast tissue.  However, based on the information available soy protein and soy isoflavones have much more positive evidence of influence than negative.  If a consumer has breast cancer (or is at very high risk), it always important to advise them to consult with their health care practitioner before taking any supplements. Remember, diet and supplements in variety and moderation always proves to be the link to a safe and healthy body.

Isoflavone Content of Various Foods
(Mean value: units=mg/100 g or 3.5 ounces edible portion)

Food Item Daidzein Genistein Total Isoflavones
Soy cheese  11.24 20.08 31.32
Soymilk, fluid 4.45 6.06 9.65
Soybeans, mature, boiled (Edamameh) 26.95 27.71 54.66
Tempeh 17.59 24.85 43.52
Tofu, extra firm, streamed 12.75 1.95 22.70
Tofu, fried (aburage) 17.83 28.00 48.35
Supro® Soy Protein Isolate powders (VL 962 & 968) 18.00 36.00 60.00
Note: per 1 serving (28 g)
Ultimate Soy-Spirulina Protein Powders (VL 964 & 956) 11.00 22.00 36.00
Note: per 1 serving (30 g)
NovaSoy® Soy Isoflavone Tablets (VL 144) Natural ratio (Varies) Natural ratio (Varies) 50 MG
Note: per tablet

*USDA-Iowa State University Isoflavones Database-1999

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